|
April 2025 |
AACR (American Association of Cancer Research) Annual meeting |
"ON" state pan-KRAS direct inhibitors |
KRAS |
Read More |
|
Feb 2023 |
Scientific Reports |
Alleviation of arthritis through prevention of neutrophil extracellular traps by an orally available inhibitor of protein arginine deiminase 4 |
PAD4 |
Read More |
|
Jan 2023 |
PLOS ONE |
Novel dual LSD1/HDAC6 inhibitor for the treatment of cancer |
Dual LSD1/HDAC6 |
Read More |
|
Nov 2022 |
Society for Immunotherapy of Cancer’s (SITC) |
Novel, brain penetrant small molecule inhibitor of PD-L1 for targeting glioblastoma and brain metastasis |
PD-L1 |
Read More |
|
Nov 2022 |
Society for Immunotherapy of Cancer’s (SITC) |
Novel, gut-restricted small molecule inhibitor of PD-L1 for targeting GI cancers |
PD-L1 |
Read More |
|
Nov 2022 |
EORTC |
Novel, brain penetrant small molecule inhibitor of PD-L1 for targeting glioblastoma and brain metastasis |
PD-L1 |
Read More |
|
Sep 2022 |
Cancer Research |
Regulation of tumor progression by PAD4-mediated neutrophil migration and its targeting with a novel selective inhibitor JBI-589 |
PAD4 |
Read More |
|
June 2022 |
American Society of Clinical Oncology (ASCO) Annual Meeting |
Novel brain penetrant inhibitors of PD-L1 |
PD-L1 |
Read More |
|
April 2022 |
AACR (American Association of Cancer Research) Annual meeting |
Novel, selective PAD4 inhibitor for treatment of cancer |
PAD4 |
Read More |
|
April 2021 |
AACR (American Association of Cancer Research) Annual meeting |
Novel, small molecule PRMT5 Inhibitors for treatment of cancer |
PRMT5 |
Read More |
|
April 2021 |
AACR (American Association of Cancer Research) Annual meeting |
Novel, heterocyclic small molecule inhibitors of PD-1/PD-L1 pathway |
PD-L1 |
Read More |
|
Dec 2020 |
Bioorg Med Chem Lett. 2020 Dec 24;34:127763 |
Novel dual LSD1/HDAC6 inhibitors for the treatment of multiple myeloma |
Dual LSD1/HDAC6 |
Read More |
|
Dec 2020 |
The 62nd ASH (American Society oh Hematology) Annual Meeting and Exposition |
JBI-802: Novel LSD1/HDAC6 inhibitor with a unique mechanism of action |
Dual LSD1/HDAC6 |
Read More |
|
April 2020 |
AACR (American Association of Cancer Research) Annual meeting |
Novel dual small molecule inhibitor targeting LSD1/HDAC6/8 |
Dual LSD1/HDAC6 |
Read More |
|
Nov 2019 |
ACR (American College of Rheumatology)/ARP Annual Meeting |
Novel PAD4 inhibitors for the treatment of autoimmune disorders |
PAD4 |
Read More |
|
April 2019 |
AACR (American Association of Cancer Research) Annual meeting |
Novel dual small molecule inhibitor targeting LSD1/HDAC6/8 |
Dual LSD1/HDAC6 |
Read More |