Leveraging Innovation To Deliver Precision Medicines

Pipeline

Overview

Applying an advanced, powerful discovery engine for novel target discovery and candidate selection

 

Unlocking the value of first-in-class and technically challenging drug targets

Disease Focus
Oncology
Auto-immune

Mechanism
Gene location/fusion protein
Driver mutations
Target overexpression
Synthetic lethality

Clinical Impact
Address tumors with specific genetic mutations
Sensitize cancers to standard of care
Overcome resistance

Benefits
First-in-class/innovator status
Fast-track/breakthrough potential
Rapid path to patients and value

Differentiated portfolio advancing towards Phase 1: multiple pre-clinical programs against validated targets considered intractable by conventional discovery approaches

LSD1/HDAC6     PD-L1    PRMT5   PAD4

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