Leveraging Innovation for Precision Medicine

Pipeline

Overview

Unlocking the value of first-in-class and technically challenging drug targets

Disease Focus
Oncology
Auto-immune

Mechanism
Gene location/fusion protein
Driver mutations
Target overexpression
Synthetic lethality

Clinical Impact
Address tumors with specific genetic mutations
Sensitize cancers to standard of care
Overcome resistance

Benefits
First-in-class/innovator status
Fast-track/breakthrough potential
Rapid path to patients and value

Broad Pipeline of Differentiated Assets with Improved Therapeutic Index

pipeline portfolio

pipeline portfolio

LSD1/HDAC6     PRMT5   PAD4   PD-L1

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